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Journal of Renin-Angiotensin-Aldosterone System
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Hypertension and its management: a problem in need of new treatment strategies

Joel M Neutel

Veterans Affairs Medical Center, Long Beach, California, University of California, Irvine, USA, JMNeutel@ aol.com

Although treatments of hypertension have significantly decreased morbidity and mortality from cerebrovascular disease, the associated reductions in coronary artery disease have been very disappointing. Hypertension is a complex inherited syndrome of cardiovascular risk factors, all of which contribute to the development of heart disease. Angiotensin II receptor blockers (ARBs), such as the highly selective ARB valsartan, provide an alternative treatment strategy to address the multiple issues in coronary artery disease. These agents are well-tolerated and have a once-daily regimen that improves compliance. They bring multiple cardiovascular benefits beyond blood pressure (BP) control, such as renoprotection and cardiovascular growth reduction.

Key Words: antihypertensive treatments • compliance • adverse events • systolic blood pressure • combination therapy

Journal of Renin-Angiotensin-Aldosterone System, Vol. 1, No. 2 suppl, S10-S13 (2000)
DOI: 10.3317/jraas.2000.046
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