SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Journal of Renin-Angiotensin-Aldosterone System
This Article
Right arrow Free Full Text (Free PDF) Free
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Sierra, C.
Right arrow Articles by Ruilope, L. M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sierra, C.
Right arrow Articles by Ruilope, L. M
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

New-onset diabetes and antihypertensive therapy: comments on ALLHAT trial

Cristina Sierra

Hypertension Units, Hospital Clinic of Barcelona & Hospital Doce de Octubre, Madrid, Spain

Luis M Ruilope

Hypertension Units, Hospital Clinic of Barcelona & Hospital Doce de Octubre, Madrid, Spain, Luis_m_Ruilope{at}teleline.es

The development of new-onset diabetes is frequent during the follow-up of treated hypertensive patients. The prevalence of such an event seems to differ depending on the type of antihypertensive therapy used to control blood pressure. Diuretics and -blockers and their association are particularly harmful in this regard. On the contrary, calcium channel blockers, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, alone or in association with diuretics, are associated with a lower prevalence of this metabolic complication. These statements are confirmed by data from the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) study. Longterm studies are required to determine the relevance of development of new-onset diabetes in treated hypertensive patients.

Key Words: new-onset diabetes • arterial hypertension • antihypertensive therapy • diuretics • angiotensin receptor blockers

Journal of Renin-Angiotensin-Aldosterone System, Vol. 4, No. 3, 169-170 (2003)
DOI: 10.3317/jraas.2003.026
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 HypertensionHome page
A. J. Zillich, J. Garg, S. Basu, G. L. Bakris, and B. L. Carter
Thiazide Diuretics, Potassium, and the Development of Diabetes: A Quantitative Review
Hypertension, August 1, 2006; 48(2): 219 - 224.
[Abstract] [Full Text] [PDF]

Home page
 HypertensionHome page
A. M. Sharma
Is There a Rationale for Angiotensin Blockade in the Management of Obesity Hypertension?
Hypertension, July 1, 2004; 44(1): 12 - 19.
[Abstract] [Full Text] [PDF]


Advertisement