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Journal of Renin-Angiotensin-Aldosterone System
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Editorial

The HOPE Study (Heart Outcomes Prevention Evaluation)

Peter Sleight

Department of Cardiovascular Medicine, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK

Key Words: HOPE • angiotensin converting enzyme inhibitors • cardiovascular morbidity • mortality • cardiovascular risk

References

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  • The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. New Engl J Med 1992; 327: 685-691.[Abstract]
  • The SOLVD Investigators. Effect of enalapril on survival in patients with reduced ejection fractions and congestive heart failure. New Engl J Med 1991; 325: 293-302.[Abstract]
  • Pfeffer MA, Braunwald L., Moye LA et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. New Engl J Med 1992; 327: 669-677.[Abstract]
  • The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on death from cardiovascular causes, myocardial infarction and stroke in high-risk patients. New Engl J Med 2000; 342:145-153.[Abstract/Free Full Text]
  • The Heart Outcomes Prevention Evaluation Study Investigators. Vitamin E supplementation and cardiovascular events in high risk patients. New Engl J Med 2000; 342:154-160.[Abstract/Free Full Text]
  • The Heart Outcomes Prevention Evaluation (HOPE) Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and Micro-HOPE substudy. Lancet 2000; 355: 253-259.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Hansson L., Lindholm LH, Niskanen L. et al. Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: The Captopril Prevention Project (CAPP) randomised trial. Lancet 1999; 353: 611-616.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Francis GS ACE inhibition in cardiovascular disease. New Engl J Med 2000; 342: 201-202.[Free Full Text]
  • Hansson L., Zanchetti A., Carruthers SG et al, for the HOT Study Group. Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 1998;351: 1755-1762.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • UK Prospective Diabetes Study (UKPDS) Group. Tight blood pressure control and risk of macrovascular complications in type-2 diabetes: UKPDS 38. Br Med J 1998;317:703-713.[Abstract/Free Full Text]
  • Hansson L., Lindholm LH, Ekbom T. et al, for the STOP-Hypertension-2 Study Group. Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study. Lancet 1999; 354: 1751-1756.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Staessen JA, Fagard B.,Thijs L. et al, for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. Lancet 1997; 350: 757-764.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]

Journal of Renin-Angiotensin-Aldosterone System, Vol. 1, No. 1, 18-20 (2000)
DOI: 10.3317/jraas.2000.002


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This Article
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Citing Articles
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Right arrow Articles by Sleight, P.
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PubMed
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*Compound via MeSH
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