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Journal of Renin-Angiotensin-Aldosterone System
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Editorial

Angiotensin II receptor blockers in chronic heart failure - Not as ELITE as expected!

Colin AJ Farquharson

University Department of Clinical, Pharmacology and Therapeutics, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK, farquharson@ dundee.ac.uk

Allan D Struthers

University Department of Clinical, Pharmacology and Therapeutics, Ninewells Hospital and Medical School, Dundee, DD1 9SY, UK

Key Words: heart failure • mortality • angiotensin II • angiotensin converting enzyme

References

  • Pitt B., Segal R., Martinez FA et al. Randomised trial of losartan vs captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE). Lancet 1997;349:747-752.2.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Pitt B., Poole-Wilson P., Segal R. et al. Effects of Losartan versus Captopril on mortality in patients with symptomatic heart failure: rationale, design, and baseline characteristics of patients in the Losartan Heart Failure Survival Study - ELITE II. J Cardiac Failure 1999;5:146-154.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Pfeffer M., Swedberg K., Granger C. et al. Candesartan in Heart failure Assessment of Reduction in Mortality and morbidity (CHARM). J Cardiac Failure 1999;5:276-282.[CrossRef][Medline] [Order article via Infotrieve]
  • Dickstein K., Kjekshus J., OPTIMAAL Study Group Comparison of the effects of losartan and captopril on mortality in patients following acute myocardial infarction: the OPTIMAAL trial design. Optimal Therapy in Myocardial Infarction with the Angiotensin II Antagonist Losartan. Am J Cardiol 1999;83:477-481.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • Cohn JN,Tognoni G., Glazer RD et al. Rationale and design of the Valsartan Heart Failure Trial: a large multinational trial to assess the effects of valsartan, an angiotensin-receptor blocker, on morbidity and mortality in chronic congestive heart failure. J Cardiac Failure 1999;5:155-160.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
  • McKelvie RS,Yusuf S., Pericak D. et al. Comparison of candesartan, enalapril and their combination in congestive heart failure: Randomised Evaluation of Strategies for Left Ventricular Dysfunction (RESOLVD) Pilot Study. Circulation 1999;100:1056-1064.[Abstract/Free Full Text]
  • Rousseau MF, Konstam MA, Benedict CR et al. Progression of left ventricular dysfunction secondary to coronary artery disease, sustained neurohormonal activation and effects of ibopamine therapy during long-term therapy with angiotensin-converting enzyme inhibitor. Am J Cardiol 1994;73:489-493.
  • Urata H., Boehm KD, Phillip A. et al. Cellular localisation and regional distribution of an angiotensin II-forming chymase in the heart. J Clin Invest 1993;91:1269-1281.[Web of Science][Medline] [Order article via Infotrieve]
  • Seyedi N.,Win T.,Lander HM, Levi R. Bradykinin B2-receptor activation augments norepinephrine exocytosis from cardiac sympathetic nerve endings. Mediation by autocrine / paracrine mechanisms. Circ Res 1997;81:774-784.[Abstract/Free Full Text]
  • Minisi AJ, Thames MD Distribution of left ventricular sympathetic afferent demonstrated by reflex responses to transmural myocardial ischaemia and to intracoronary and epicardial bradykinin. Circulation 1993;87:240-246.[Abstract/Free Full Text]

Journal of Renin-Angiotensin-Aldosterone System, Vol. 1, No. 1, 21-22 (2000)
DOI: 10.3317/jraas.2000.003


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This Article
Right arrow Free Full Text (Free PDF) Free
Right arrow Alert me when this article is cited
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Services
Right arrow Email this article to a friend
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Right arrow Similar articles in PubMed
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Right arrow Add to Saved Citations
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Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Farquharson, C. A.
Right arrow Articles by Struthers, A. D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Farquharson, C. A.
Right arrow Articles by Struthers, A. D
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