|
Sign In to gain access to subscriptions and/or personal tools.
|
Review: Signal transduction mechanisms of the angiotensin II type AT1-receptor: looking beyond the heterotrimeric G protein paradigm
Peter P Sayeski
Department of Physiology, University of Florida College of Medicine, PO Box 100274, Gainesville, FL 32610 USA
Kenneth E Bernstein
Department of Pathology & Laboratory Medicine, Emory University School of Medicine, 1639 Pierce Drive, 7107 WMB, Atlanta, GA 30322 USA, kbernst{at}emory.edu
Key Words: hypertension nephroangiosclerosis regression of fibrosis extracellular matrix
References
- Duncia JV, Carini DJ, Chiu AT et al. The discovery of Dup753, a potent, orally active nonpeptide Ang II receptor antagonist. Med Res Rev 1992;12:149-91.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Chiu AT, McCall DE, Nguyen TT et al. Discrimination of Ang II receptor subtypes by dithiothreitol. Eur J Pharm 1989;170:117-8.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Wong PC, Price WA, Chiu AT et al. In vivo pharmacology of Dup753. Am J Hypertens 991;4:S288-98.
- Timmermans Pbmwm, Wong PC, Chiu AT et al. Ang II receptors and Ang II receptor antagonists. Pharm Rev 1993;45:205-51.[Web of Science][Medline]
[Order article via Infotrieve]
- Ondetti MA, Rubin B., Cushman DW Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active anti-hypertensive agents. Science 1977;196:441-4.[Abstract/Free Full Text]
- Teerlink JR The evolving role of angiotensin-converting enzyme inhibition in heart failure: expanding the protective envelope.J Cardiovasc Pharmacol 1994;24:S32-7.[Web of Science][Medline]
[Order article via Infotrieve]
- Fouad-Tarazi FM Hemodynamic effects of inhibitors of the renin-angiotensin system. J Hypertension 1994;12:S25-S29.
- Daemen MJ, Lombardi DM, Bosman FT, Schwartz SM Ang II induces smooth muscle proliferation in the normal and injured rat arterial wall. Circ Res 1991;68:450-6.[Abstract/Free Full Text]
- The Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting enzyme inhibitor, ramipril, on death from cardiovascular causes, myocardial infarction, and stroke in high risks patients. New Engl J Med 2000;342:145-53.[Abstract/Free Full Text]
- The Heart Outcomes Prevention Evaluation Study Investigators. Vitamin E supplementation and cardiovascular events in high risk patients. New Engl J Med 2000;342:154-60.[Abstract/Free Full Text]
- Regan CP, Bishop SP, Berecek KH Early, short-term treatment with captopril permanently attenuates cardiovascular changes in spontaneously hypertensive rats. Clin Exp Hypertens 1997;19:1161-77.[Web of Science][Medline]
[Order article via Infotrieve]
- Katovich MJ, Gelband CH, Reaves PY, Wang HW, Raizada MK Reversal of hypertension by Ang II type 1 receptor antisense gene in the adult spontaneously hypertensive rat. Amer J Physiol 1999;277:H1260-4.
- Reaves PY, Gelband CH, Wang HW et al. Permanent cardiovascular protection from hypertension by the AT1 receptor antisense gene therapy in hypertensive rat offspring. Circ Res 1999;85:44-50.
- Pachori AS, Wang HW, Gelband CH, Ferrario CM, Katovich MJ, Raizada MK Inability to induce hypertension in normotensive rat expressing AT1 receptor antisense. Circ Res 2000;86:1167-72.[Abstract/Free Full Text]
- Katz AM Is Ang II a growth factor masquerading as a vasopressor? Heart Dis Stroke 1992;1:151-4.[Medline]
[Order article via Infotrieve]
- Powell JS, Clozel JP, Muller RK, Kuhn H., Hefti F., Hosang M. Inhibitors of angiotensin converting enzyme prevent myointimal proliferation after vascular injury. Science 1989;245:186-8.[Abstract/Free Full Text]
- Chiu AT, Roscoe WA, McCall DE, Timmermans Pbmwm. Ang II type-1 receptors mediate both vasoconstrictor and hypertrophic responses in rat aortic smooth muscle cells. Receptors 1991;1:133-40.
- Hein L., Stevens ME, Barsh GS, Pratt RE, Kobilka BK, Dzau VJ Over expression of angiotensin AT1 receptor transgene in the mouse myocardium produces a lethal phenotype associated with myocyte hyperplasia and heart block. Proc Natl Acad Sci (USA) 1997;94:6391-6.[Abstract/Free Full Text]
- Paradis P., Dali-Youcef N., Paradis FW,Thibault G., Nemer M. Overexpression of Ang II type 1 receptor in cardiac myocytes induces cardiac hypertrophy and remodeling. Proc Natl Acad Sci (USA) 2000;97:931-6.[Abstract/Free Full Text]
- Pawson T. New impressions of Src and Hck. Nature 1997;385:582-3.[Web of Science][Medline]
[Order article via Infotrieve]
- Sasaki K., Yamano Y., Bardhan S. et al. Cloning and expression of a complementary cDNA encoding a bovine adrenal Ang II type-1 receptor.Nature 1991;351:230-2.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Murphy TJ, Alexander RW, Griendling KK, Runge MS, Bernstein KE Isolation of a cDNA encoding the vascular type-1 Ang II receptor. Nature 1991;351:233-6.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Dhar A., Shukla SD Electrotransjection of pp60v-src monoclonal antibody inhibits activation of phospholipase C in platelets. J Biol Chem 1994;269:9123-7.[Abstract/Free Full Text]
- Erpel T., Courtneidge SA Src family protein tyrosine kinases and cellular signal transduction. Curr Opin Cell Biol 1995;7:176-82.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Peeler TC, Conrad KM, Baker KM Endothelin stimulates sis-inducing factor-like DNA binding activity in CHO-K1 cells expressing ETA receptors. Biochem Biophys Res Comm 1996;221:62-6.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Buggy JJ Binding of
-melanocyte-stimulating hormone to its G protein-coupled receptor on B-lymphocytes activates the Jak/STAT pathway. Biochem J1998;331:211-6. - Luttrell LM, Ferguson SSG, Daaka Y. et al. β-arrestin dependent formation of β2 adrenergic receptor-Src protein kinase complexes. Science 1999;283:655-61.1.[Abstract/Free Full Text]
- Sasaguri T., Teruya H., Ishida A., Abumiya T., Ogata J. Linkage between
1 adrenergic receptor and the Jak/STAT signaling pathway in vascular smooth muscle cells. Biochem Biophys Res Comm 2000;268:25-30.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve] - Zhong H., Murphy TJ, Minneman KP Activation of signal transducers and activators of transcription by
1A-adrenergic receptor stimulation in PC12 cells. Mol Pharm 2000;5:961-7. - Marrero MB, Scheiffer B., Paxton WG et al. Direct stimulation of Jak/STAT pathway by the Ang II AT1 receptor. Nature 1995;375:247-50.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Sadoshima J., Izumo S. The heterotrimeric G
protein-coupled Ang II receptor activates p21ras via the tyrosine kinase-Shc-Grb2-Sos pathway in cardiac myocytes. EMBO J 1996;15:775-87.[Web of Science][Medline]
[Order article via Infotrieve] - Ishida M., Marrero MB, Schieffer B., Ishida T., Bernstein KE, Berk BC Ang II activates pp60c-src in vascular smooth muscle cells. Circ Res 1995;77:1053-9.[Abstract/Free Full Text]
- Li X., Earp HS Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells. J Biol Chem 1997;272:14341-8.[Abstract/Free Full Text]
- Ali MS, Sayeski PP, Dirksen LB, Hayzer DJ, Marrero MB, Bernstein KE Dependence of the motif YIPP for the physical association of Jak2 kinase with the intracellular carboxyl tail of the Ang II AT1 receptor. JBiol Chem 1997;272:23382-8.[Abstract/Free Full Text]
- Murakami M., Narazaki M., Hibi M. et al. Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor superfamily.Proc Natl Acad Sci (USA) 1991;88:11349-53.[Abstract/Free Full Text]
- Zhu YX, Sun HB, Tsang MLS et al. Critical cytoplasmic domains of the human interleukin-9 receptor
chain in interleukin-9-mediated cell proliferation and signal transduction. J Biol Chem 1997;272:21334-40.[Abstract/Free Full Text] - Ali MS, Sayeski PP, Bernstein KE Jak2 acts as both a STAT1 kinase and as a molecular bridge linking STAT1 to the angiotensin II AT1 receptor. J Biol Chem 2000;275:15586-93.[Abstract/Free Full Text]
- Sayeski PP,Ali MS, Safavi A. et al. A catalytically active Jak2 is required for the Ang II-dependent activation of Fyn. J Biol Chem 1999;274:33131-42.[Abstract/Free Full Text]
- Ali MS, Sayeski PP, Safavi A., Lyles M., Bernstein KE Janus kinase 2 (Jak2) must be catalytically active to associate with the AT1 receptor in response to Ang II. Biochem Biophys Res Comm 1998;249:672-7.[CrossRef][Web of Science][Medline]
[Order article via Infotrieve]
- Taubman MB, Berk BC, Izumo S., Tsuda T., Alexander RW, Nadal-Ginard B. Ang II induces c-fos mRNA in aortic smooth muscle cells. JBiol Chem 1989;264:526-30.[Abstract/Free Full Text]
Journal of Renin-Angiotensin-Aldosterone System, Vol. 2, No. 1,
4-10 (2001)
DOI: 10.3317/jraas.2001.007

CiteULike Complore Connotea Del.icio.us Digg Reddit Technorati Twitter What's this?
This article has been cited by other articles:

|
 |

|
 |
 
M. Paul, A. Poyan Mehr, and R. Kreutz
Physiology of local Renin-Angiotensin systems.
Physiol Rev,
July 1, 2006;
86(3):
747 - 803.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
J. L. Lavoie and C. D. Sigmund
Minireview: Overview of the Renin-Angiotensin System--An Endocrine and Paracrine System
Endocrinology,
June 1, 2003;
144(6):
2179 - 2183.
[Abstract]
[Full Text]
[PDF]
|
 |
|

|
 |

|
 |
 
I. Manabe, T. Shindo, and R. Nagai
Gene Expression in Fibroblasts and Fibrosis: Involvement in Cardiac Hypertrophy
Circ. Res.,
December 13, 2002;
91(12):
1103 - 1113.
[Abstract]
[Full Text]
[PDF]
|
 |
|
|
|