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Grossly elevated serum angiotensin-converting enzyme activities are still suppressible with ACE inhibitor therapy
Miles D Witham
Section of Ageing and Health, Ninewells Hospital,, m.witham@ dundee.ac.uk
Stuart D Hutcheon
Raigmore Hospital, Inverness, Scotland
Callum G Fraser
Department of Biochemical Medicine, Ninewells Hospital
Marion ET McMurdo
Department of Biochemical Medicine, Ninewells Hospital
Allan D Struthers
Department of Clinical Pharmacology, Ninewells Hospital, Dundee, Scotland
Key Words: serum ACE angiotensin-converting enzyme inhibitors
References
- Studdy PR, Lapworth R., Bird R. Angiotensin-converting enzyme and its clinical significance - a review. J Clin Pathol 1983;36:938-47.[Abstract/Free Full Text]
- Kramers C., Danilov SM, Deinum J. et al. Point mutation in the stalk of angiotensin-converting enzyme causes a dramatic increase in serum angiotensin-converting enzyme but no cardiovascular disease. Circulation 2001;104:1236-40.[Abstract/Free Full Text]
- Struthers AD, MacFadyen R., Fraser C. et al. Nonadherence with angiotensin-converting enzyme inhibitor therapy: a comparison of different ways of measuring it in patients with chronic heart failure. J Am Coll Cardiol 1999;34:2072-7.[Abstract/Free Full Text]
- Struthers AD, Anderson G., MacFadyen RJ, Fraser C., MacDonald TM Non-adherence with ACE inhibitor treatment is common in heart failure and can be detected by routine serum ACE activity assays. Heart 1999;82:584-8.[Abstract/Free Full Text]
- Lieberman J., Zakria F. Effect of captopril and enalapril medication on the serum ACE test for sarcoidosis. Sarcoidosis 1989;6:118-23.[Medline]
[Order article via Infotrieve]
Journal of Renin-Angiotensin-Aldosterone System, Vol. 3, No. 2,
138 (2002)
DOI: 10.3317/jraas.2002.017

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