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ASCOT a Four Horse Race
Peter Sever
NHLI Division Imperial College London International Centre for Circulatory Health, 59-61 North Wharf Road, London, W2 1NY, UK, p.sever{at}imperial.ac.uk
References
- Dahlöf B., Sever PS, Poulter NR et al; for the ASCOT Investigators. Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA): a multicentre randomised controlled trial. Lancet 2005;366:895-906.[CrossRef][Web of Science][Medline]
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- Poulter NR, Wedel H., Dahlöf B. et al; for the ASCOT Investigators Role of blood pressure and other variables in the differential cardiovascular event rates noted in the Anglo-Scandinavian Cardiac Outcomes Trial-Blood Pressure Lowering Arm (ASCOT-BPLA). Lancet 2005;366:907-13[CrossRef][Web of Science][Medline]
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- Furberg CD, Psaty BM Should calcium antagonists be first-line agents in the treatment of cardiovascular disease? The public health perspective. Cardiovasc Drugs Ther 1996; 10:463-6.[CrossRef][Web of Science][Medline]
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- Sever PS, Dahlöf B., Poulter NR et al; for the ASCOT investigators. Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial - Lipid lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial. Lancet 2003;361:1149-58.[CrossRef][Web of Science][Medline]
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- Williams B., Poulter NR, Brown MJ et al; BHS guidelines working party, for the British Hypertension Society. British Hypertension Society guidelines for hypertension management 2004 (BHS-IV): summary. BMJ 2004;328:634-40.[Free Full Text]
- Hypertension Detection and Follow-up Programme Cooperative Group (HDFP). Five-year findings of the Hypertension Detection and Follow-up Programme: reduction in mortality in persons with high blood pressure, including mild hypertension. JAMA 1979;242:2562-571.[Abstract/Free Full Text]
- Heart Outcomes Prevention Evaluation Study Investigators (HOPE). Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Lancet 2000;355:253-9.[CrossRef][Web of Science][Medline]
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- Williams B. The renin angiotensin system and cardiovascular disease: hope or hype? JRAAS 2000;2:142-6.
- Staessen JA, Thijs L., Birkenhager WH Evidence that new antihypertensives are superior to older drugs. Lancet 2005; 366:869-70.[CrossRef][Web of Science][Medline]
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- Staessen JA, Li Y., Thijs L., Wang JG Blood pressure reduction and cardiovascular prevention: an update including the 2003-2004 secondary prevention trials. Hypertens Res 2005;28:385-407.[CrossRef][Web of Science][Medline]
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- ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs. diuretic. JAMA 2002;23:2981-97.
- Julius S., Kjeldsen SE, Weber M. et al. Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004;363:2022-31.[CrossRef][Web of Science][Medline]
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Journal of Renin-Angiotensin-Aldosterone System, Vol. 6, No. 2,
51-54 (2005)
DOI: 10.3317/jraas.2005.010

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