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Resolving the mysteries of the renin-angiotensin system in diabetes

Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

References

• Luetscher JA, Kraemer FB, Wilson DM, Schwartz HC, Bryer-Ash M. Increased plasma inactive renin in diabetes mellitus: a marker of microvascular complications. N Engl J Med 1985; 312:1412-17.[Abstract]
• Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001;345:851-60.[Abstract/Free Full Text]
• Brenner BM, Cooper ME, deZeeuw D. et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001;345:861-9.[Abstract/Free Full Text]
• Veniant M., Menard J., Bruneval P., Morley S., Gonzales MF, Mullins J. Vascular damage without hypertension in transgenic rats expressing prorenin exclusively in the liver. J Clin Invest 1996;98:1966-70.[Web of Science][Medline] [Order article via Infotrieve]
• Kim S., Hosoi M., Nakajima K., Yamamoto K. Immunological evidence that kidney is primary source of circulating inactive prorenin in rats. Am J Physiol Renal Physiol 1991; 260:E526-E536.
• Nguyen G., Delarue F., Burckle C., Bouzhir L., Giller T., Sraer J.-D. Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin. J Clin Invest 2002;109:1417-27.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
• Suzuki F., Hayakawa M., Nakagawa T. et al. Human prorenin has `gate and handle` regions for its non-proteolytic activation. J Biol Chem 2003;278:22217-22.[Abstract/Free Full Text]
• Ichihara A., Kaneshiro Y., Suzuki F. Prorenin receptor blockers: effects on cardiovascular complications of diabetes and hypertension. Expert Opin Investig Drugs 2006;15:1137-9.[CrossRef][Web of Science][Medline] [Order article via Infotrieve]
• Ichihara A., Kaneshiro Y., Takemitsu T. et al. Non-proteolytic activation of prorenin contributes to development of cardiac fibrosis in genetic hypertension. Hypertension 2006;47:894-900.[Abstract/Free Full Text]
• Ichihara A., Kaneshiro Y., Takemitsu T. et al. Contribution of non-proteolytically activated prorenin in glomeruli to hypertensive renal damage. J Am Soc Nephrol 2006;17:2495-503.[Abstract/Free Full Text]
• Ichihara A., Suzuki F., Nakagawa T. et al. Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor deficient mice. J Am Soc Nephrol 2006;17:1950-61.[Abstract/Free Full Text]

Journal of Renin-Angiotensin-Aldosterone System, Vol. 7, No. 4, 250-251 (2006)
DOI: 10.1177/14703203060070040201


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This Article Free Full Text (Free PDF) Free Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Ichihara, A. Search for Related Content PubMed Articles by Ichihara, A. Social Bookmarking                         What's this?